Please provide your email address to receive an email when new articles are posted on . Historically marginalized populations may see underdiagnosed rates of inborn errors of immunity. Barriers beyond ...

Please provide your email address to receive an email when new articles are posted on . Black patients had the greatest odds for death before age 65 years. Hispanic vs. non-Hispanic patients had ...

Inherited diseases of metabolism and immunity have more in common than previously recognized, according to a new study. The findings point to a new set of metabolic genes that are important for the ...

Behind every unexplained medical condition is a patient hoping for clarity and understanding. For people with suspected inborn errors of immunity (IEIs), genetic testing can facilitate individually ...

A new report says early evidence of using gene therapy to treat monogenic diseases offers reason for optimism. Gene therapy (GT) holds significant potential to help correct monogenic diseases, ...

In vitro and animal model studies conducted by scientists at the University College London (UCL) have demonstrated the feasibility of a gene therapy approach to correct the deficiency of a regulatory ...

The OS and GEFS of the study cohort. The solid line and the dashed line show OS and GEFS curves, respectively. OS and GEFS at 2 years post-HCT are described with 95% confidence intervals in brackets.

Dr Alessandro Borghesi’s research, currently conducted across Italy and Switzerland, focuses on identifying monogenic conditions — or their autoimmune phenocopies — that may lead to immune ...

Innate immune sensors – known as pattern recognition receptors (PRRs) – detect specific molecular components of bacterial or viral intruders. The PRRs forward the signals which results in the ...