Recruitment of ribosomes to mRNA templates is generally the rate-limiting step of translation initiation and is mediated by eukaryotic initiation factor (eIF) 4F—a heterotrimeric complex consisting of ...

eIF4F is an upstream regulator of PD-L1 expression and a promising target for improved immunotherapies Immune evasion by cancer cells through activation of inhibitory checkpoints has become a key ...

Cancer is the Houdini of diseases because it escapes elaborately contrived predicaments. Like Houdini, who was known to emerge triumphant after being handcuffed, locked in a trunk, and tossed into a ...

Efficacy of ocaratuzumab (AME-133v) in relapsed follicular lymphoma patients refractory to prior rituximab. Use of the cumulative amount of serum-free light chains (sFLC) at diagnosis and PET2 for the ...